Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency

CONTEXT: Decreased vitamin B12 concentration does not usually result in clinical or hematological abnormalities. Subacute combined spinal cord degeneration and pancytopenia are two serious and rarely displayed consequences that appear in severe deficits. CASE REPORT: We present the case of a patient...

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Autores principales: Cabrerizo-García, José Luis, Sebastián-Royo, Mariano, Montes, Nerea, Zalba-Etayo, Begoña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Paulista de Medicina - APM 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619957/
https://www.ncbi.nlm.nih.gov/pubmed/22965368
http://dx.doi.org/10.1590/S1516-31802012000400010
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author Cabrerizo-García, José Luis
Sebastián-Royo, Mariano
Montes, Nerea
Zalba-Etayo, Begoña
author_facet Cabrerizo-García, José Luis
Sebastián-Royo, Mariano
Montes, Nerea
Zalba-Etayo, Begoña
author_sort Cabrerizo-García, José Luis
collection PubMed
description CONTEXT: Decreased vitamin B12 concentration does not usually result in clinical or hematological abnormalities. Subacute combined spinal cord degeneration and pancytopenia are two serious and rarely displayed consequences that appear in severe deficits. CASE REPORT: We present the case of a patient with subacute combined spinal cord degeneration and pancytopenia secondary to severe and sustained vitamin B12 deficiency. Such cases are rare nowadays and have potentially fatal consequences. CONCLUSIONS: Vitamin B12 deficiency should be taken into consideration in the differential diagnosis in cases of blood disorders or severe neurological symptoms. Early diagnosis and treatment can avoid irreversible consequences.
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spelling pubmed-106199572023-11-02 Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency Cabrerizo-García, José Luis Sebastián-Royo, Mariano Montes, Nerea Zalba-Etayo, Begoña Sao Paulo Med J Case Report CONTEXT: Decreased vitamin B12 concentration does not usually result in clinical or hematological abnormalities. Subacute combined spinal cord degeneration and pancytopenia are two serious and rarely displayed consequences that appear in severe deficits. CASE REPORT: We present the case of a patient with subacute combined spinal cord degeneration and pancytopenia secondary to severe and sustained vitamin B12 deficiency. Such cases are rare nowadays and have potentially fatal consequences. CONCLUSIONS: Vitamin B12 deficiency should be taken into consideration in the differential diagnosis in cases of blood disorders or severe neurological symptoms. Early diagnosis and treatment can avoid irreversible consequences. Associação Paulista de Medicina - APM 2012-09-04 /pmc/articles/PMC10619957/ /pubmed/22965368 http://dx.doi.org/10.1590/S1516-31802012000400010 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons license.
spellingShingle Case Report
Cabrerizo-García, José Luis
Sebastián-Royo, Mariano
Montes, Nerea
Zalba-Etayo, Begoña
Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency
title Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency
title_full Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency
title_fullStr Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency
title_full_unstemmed Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency
title_short Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency
title_sort subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin b12 deficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619957/
https://www.ncbi.nlm.nih.gov/pubmed/22965368
http://dx.doi.org/10.1590/S1516-31802012000400010
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