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Autoinhibited kinesin-1 adopts a hierarchical folding pattern

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Conventional kinesin-1 is the primary anterograde motor in cells for transporting cellular cargo. While there is a consensus that the C-terminal tail of kinesin-1 inhibits motility, the molecular architecture of a full-length autoinhibited kinesin-1 remains unknown. Here, we combine crosslinking mas...

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Detalles Bibliográficos
Autores principales:	Tan, Zhenyu, Yue, Yang, Leprevost, Felipe, Haynes, Sarah, Basrur, Venkatesha, Nesvizhskii, Alexey I, Verhey, Kristen J, Cianfrocco, Michael A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619981/ https://www.ncbi.nlm.nih.gov/pubmed/37910016 http://dx.doi.org/10.7554/eLife.86776

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