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A Rare Presentation of Scurvy in a Well-Nourished Patient

Vitamin C deficiency, otherwise known as scurvy, is a rare diagnosis among populations with adequate nutritional resources. We present a 37-year-old female patient with bilateral lower extremity edema, episodic anasarca, petechiae, and easy bruising who was diagnosed with scurvy. Given the clinical...

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Autores principales: Robin, Connor J, Robin, Kaleb J, Maier, Mark A, Stevens, Elyse S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620061/
https://www.ncbi.nlm.nih.gov/pubmed/37927702
http://dx.doi.org/10.7759/cureus.46379
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author Robin, Connor J
Robin, Kaleb J
Maier, Mark A
Stevens, Elyse S
author_facet Robin, Connor J
Robin, Kaleb J
Maier, Mark A
Stevens, Elyse S
author_sort Robin, Connor J
collection PubMed
description Vitamin C deficiency, otherwise known as scurvy, is a rare diagnosis among populations with adequate nutritional resources. We present a 37-year-old female patient with bilateral lower extremity edema, episodic anasarca, petechiae, and easy bruising who was diagnosed with scurvy. Given the clinical presentation, a broad differential was investigated with no findings suggestive of hematologic or cardiovascular pathology. Initial laboratory studies were unremarkable. Progression of cutaneous symptoms and subsequent laboratory findings demonstrating low vitamin C levels supported a diagnosis of scurvy. Classical symptoms of scurvy include mucocutaneous petechiae, poor wound healing, ecchymosis, hyperkeratosis, corkscrew hair, gingival swelling, and bleeding gums. Following standard enteral supplementation of vitamin C, repeat vitamin C levels failed to adequately respond with the patient remaining to be symptomatic. Given a lack of insufficient nutritional intake or known systemic illness, gastrointestinal malabsorptive etiology was suspected. Though rare in the United States, scurvy should be considered in patients with manifestations of a bleeding disorder. A gastrointestinal workup may be indicated if other nutritional deficiencies are identified, or a source of inadequate intake cannot be established.
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spelling pubmed-106200612023-11-03 A Rare Presentation of Scurvy in a Well-Nourished Patient Robin, Connor J Robin, Kaleb J Maier, Mark A Stevens, Elyse S Cureus Gastroenterology Vitamin C deficiency, otherwise known as scurvy, is a rare diagnosis among populations with adequate nutritional resources. We present a 37-year-old female patient with bilateral lower extremity edema, episodic anasarca, petechiae, and easy bruising who was diagnosed with scurvy. Given the clinical presentation, a broad differential was investigated with no findings suggestive of hematologic or cardiovascular pathology. Initial laboratory studies were unremarkable. Progression of cutaneous symptoms and subsequent laboratory findings demonstrating low vitamin C levels supported a diagnosis of scurvy. Classical symptoms of scurvy include mucocutaneous petechiae, poor wound healing, ecchymosis, hyperkeratosis, corkscrew hair, gingival swelling, and bleeding gums. Following standard enteral supplementation of vitamin C, repeat vitamin C levels failed to adequately respond with the patient remaining to be symptomatic. Given a lack of insufficient nutritional intake or known systemic illness, gastrointestinal malabsorptive etiology was suspected. Though rare in the United States, scurvy should be considered in patients with manifestations of a bleeding disorder. A gastrointestinal workup may be indicated if other nutritional deficiencies are identified, or a source of inadequate intake cannot be established. Cureus 2023-10-02 /pmc/articles/PMC10620061/ /pubmed/37927702 http://dx.doi.org/10.7759/cureus.46379 Text en Copyright © 2023, Robin et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Robin, Connor J
Robin, Kaleb J
Maier, Mark A
Stevens, Elyse S
A Rare Presentation of Scurvy in a Well-Nourished Patient
title A Rare Presentation of Scurvy in a Well-Nourished Patient
title_full A Rare Presentation of Scurvy in a Well-Nourished Patient
title_fullStr A Rare Presentation of Scurvy in a Well-Nourished Patient
title_full_unstemmed A Rare Presentation of Scurvy in a Well-Nourished Patient
title_short A Rare Presentation of Scurvy in a Well-Nourished Patient
title_sort rare presentation of scurvy in a well-nourished patient
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620061/
https://www.ncbi.nlm.nih.gov/pubmed/37927702
http://dx.doi.org/10.7759/cureus.46379
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