Cargando…

Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain

The prefrontal cortex (PFC) is a complex brain region that regulates diverse functions ranging from cognition, emotion and executive action to even pain processing. To decode the cellular and circuit organization of such diverse functions, we employed spatially resolved single-cell transcriptome pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhattacherjee, Aritra, Zhang, Chao, Watson, Brianna R., Djekidel, Mohamed Nadhir, Moffitt, Jeffrey R., Zhang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620082/ https://www.ncbi.nlm.nih.gov/pubmed/37845544 http://dx.doi.org/10.1038/s41593-023-01455-9

Ejemplares similares

Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction
por: Bhattacherjee, Aritra, et al.
Publicado: (2019)

Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex
por: Maynard, Kristen R., et al.
Publicado: (2021)

FIND: difFerential chromatin INteractions Detection using a spatial Poisson process
por: Djekidel, Mohamed Nadhir, et al.
Publicado: (2018)

Encoding of Spatial Attention by Primate Prefrontal Cortex Neuronal Ensembles
por: Backen, Theda, et al.
Publicado: (2018)

A molecularly defined D1 medium spiny neuron subtype negatively regulates cocaine addiction
por: Zhao, Zheng-dong, et al.
Publicado: (2022)

Distinct neuronal excitability alterations of medial prefrontal cortex in early‐life neglect model of rats
por: Zhang, Yu, et al.
Publicado: (2022)

Cell type–specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis
por: Chen, Renchao, et al.
Publicado: (2022)

Multiple Distinct Subtypes of GABAergic Neurons in Mouse Visual Cortex Identified by Triple Immunostaining
por: Gonchar, Yuri, et al.
Publicado: (2008)

Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder
por: Arion, Dominique, et al.
Publicado: (2015)

Neuronal coding in the rodent prefrontal cortex
por: Kornienko, Olga, et al.
Publicado: (2013)

A transcriptional roadmap for 2C-like–to–pluripotent state transition
por: Fu, Xudong, et al.
Publicado: (2020)

Heightened cocaine-seeking in male rats associates with a distinct transcriptomic profile in the medial prefrontal cortex
por: Merritt, Christina R., et al.
Publicado: (2022)

Specialization of the Rostral Prefrontal Cortex for Distinct Analogy Processes
por: Volle, Emmanuelle, et al.
Publicado: (2010)

Neuronal congruency effects in macaque prefrontal cortex
por: Yao, Tao, et al.
Publicado: (2022)

Spatially patterned excitatory neuron subtypes and projections of the claustrum
por: Erwin, Sarah R, et al.
Publicado: (2021)

Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
por: Mitchell, Amanda C., et al.
Publicado: (2016)

Prefrontal Cortex Lesions Impair Object-Spatial Integration
por: Voytek, Bradley, et al.
Publicado: (2012)

Distinct Spiking Patterns of Excitatory and Inhibitory Neurons and LFP Oscillations in Prefrontal Cortex During Sensory Discrimination
por: Tseng, Hua-an, et al.
Publicado: (2021)

Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex
por: Huuki-Myers, Louise, et al.
Publicado: (2023)

Subtype‐specific effects of dopaminergic D2 receptor activation on synaptic trains in layer V pyramidal neurons in the mouse prefrontal cortex
por: Leyrer‐Jackson, Jonna M., et al.
Publicado: (2017)

Distinct effects of prefrontal and parietal cortex inactivations on an accumulation of evidence task in the rat
por: Erlich, Jeffrey C, et al.
Publicado: (2015)

Computational Investigation of Contributions from Different Subtypes of Interneurons in Prefrontal Cortex for Information Maintenance
por: Zhang, Qian, et al.
Publicado: (2020)

Stress Changes the Spatial Arrangement of Neurons and Glial Cells of Medial Prefrontal Cortex and Sertraline and Curcumin Prevent It
por: Noorafshan, Ali, et al.
Publicado: (2015)

Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia
por: Hagihara, Hideo, et al.
Publicado: (2014)

Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism
por: Murano, Tomoyuki, et al.
Publicado: (2017)

Transcriptome Profiling of the Dorsomedial Prefrontal Cortex in Suicide Victims
por: Dóra, Fanni, et al.
Publicado: (2022)

Decoding the role of transcriptomic clocks in the human prefrontal cortex
por: Martínez-Magaña, José J., et al.
Publicado: (2023)

Activity-dependent serotonergic excitation of callosal projection neurons in the mouse prefrontal cortex
por: Stephens, Emily K., et al.
Publicado: (2014)

Combining electrophysiology and optogenetics for functional screening of pyramidal neurons in the mouse prefrontal cortex
por: Nagahama, Kenichiro, et al.
Publicado: (2021)

Dorsolateral and dorsomedial prefrontal cortex track distinct properties of dynamic social behavior
por: McDonald, Kelsey R, et al.
Publicado: (2020)

Electrophysiological Decoding of Spatial and Color Processing in Human Prefrontal Cortex
por: Min, Byoung-Kyong, et al.
Publicado: (2021)

Neurons in primate prefrontal cortex signal valuable social information during natural viewing
por: Adams, Geoffrey K., et al.
Publicado: (2021)

Glutamatergic neurons and GABAergic neurons of medial prefrontal cortex control hoarding-like behavior
por: Xiong, Yujie, et al.
Publicado: (2023)

Localist versus distributed representation of sounds in the auditory cortex controlled by distinct inhibitory neuronal subtypes
por: Tobin, Melanie, et al.
Publicado: (2023)

The prefrontal cortex /
por: Fuster, Joaquin M.
Publicado: (2008)

Effects of arginine vasopressin on the transcriptome of prefrontal cortex in autistic rat model
por: Zhou, Bo, et al.
Publicado: (2022)

Neuron-specific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia
por: Sullivan, Courtney R., et al.
Publicado: (2018)

Spatial organization shapes the turnover of a bacterial transcriptome
por: Moffitt, Jeffrey R, et al.
Publicado: (2016)

Distinct Contributions of the Dorsolateral Prefrontal and Orbitofrontal Cortex during Emotion Regulation
por: Golkar, Armita, et al.
Publicado: (2012)

Distinct behavioural and network correlates of two interneuron types in prefrontal cortex
por: Kvitsiani, D., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_qeum797f1goou9g8j66gorivpd