Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages

Elevated plasma numbers of atherogenic apoB-lipoproteins (apoB), mostly as low-density lipoproteins (LDL), predict diabetes risk by unclear mechanisms. Upregulation of the NLRP3 inflammasome/interleukin-1 beta (IL-1β) system in white adipose tissue (WAT) is implicated in type 2 diabetes (T2D); howev...

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Detalles Bibliográficos
Autores principales: Bissonnette, Simon, Lamantia, Valérie, Ouimet, Benjamin, Cyr, Yannick, Devaux, Marie, Rabasa-Lhoret, Remi, Chrétien, Michel, Saleh, Maya, Faraj, May
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620147/
https://www.ncbi.nlm.nih.gov/pubmed/37914804
http://dx.doi.org/10.1038/s41598-023-45870-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620147/
https://www.ncbi.nlm.nih.gov/pubmed/37914804
http://dx.doi.org/10.1038/s41598-023-45870-1

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