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Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages

Elevated plasma numbers of atherogenic apoB-lipoproteins (apoB), mostly as low-density lipoproteins (LDL), predict diabetes risk by unclear mechanisms. Upregulation of the NLRP3 inflammasome/interleukin-1 beta (IL-1β) system in white adipose tissue (WAT) is implicated in type 2 diabetes (T2D); howev...

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Detalles Bibliográficos
Autores principales:	Bissonnette, Simon, Lamantia, Valérie, Ouimet, Benjamin, Cyr, Yannick, Devaux, Marie, Rabasa-Lhoret, Remi, Chrétien, Michel, Saleh, Maya, Faraj, May
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620147/ https://www.ncbi.nlm.nih.gov/pubmed/37914804 http://dx.doi.org/10.1038/s41598-023-45870-1

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