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Structure—yeast α-glucosidase inhibitory activity relationship of 9-O-berberrubine carboxylates

Thirty-five 9-O-berberrubine carboxylate derivatives were synthesized and evaluated for yeast α-glucosidase inhibitory activity. All compounds demonstrated better inhibitory activities than the parent compounds berberine (BBR) and berberrubine (BBRB), and a positive control, acarbose. The structure–...

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Detalles Bibliográficos
Autores principales: Nguyen, Duy Vu, Hengphasatporn, Kowit, Danova, Ade, Suroengrit, Aphinya, Boonyasuppayakorn, Siwaporn, Fujiki, Ryo, Shigeta, Yasuteru, Rungrotmongkol, Thanyada, Chavasiri, Warinthorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620162/
https://www.ncbi.nlm.nih.gov/pubmed/37914757
http://dx.doi.org/10.1038/s41598-023-45116-0