Combining single-cell RNA sequencing and population-based studies reveals hand osteoarthritis-associated chondrocyte subpopulations and pathways

Hand osteoarthritis is a common heterogeneous joint disorder with unclear molecular mechanisms and no disease-modifying drugs. In this study, we performed single-cell RNA sequencing analysis to compare the cellular composition and subpopulation-specific gene expression between cartilage with macrosc...

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Detalles Bibliográficos
Autores principales: Li, Hui, Jiang, Xiaofeng, Xiao, Yongbing, Zhang, Yuqing, Zhang, Weiya, Doherty, Michael, Nestor, Jacquelyn, Li, Changjun, Ye, Jing, Sha, Tingting, Lyu, Houchen, Wei, Jie, Zeng, Chao, Lei, Guanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620170/
https://www.ncbi.nlm.nih.gov/pubmed/37914703
http://dx.doi.org/10.1038/s41413-023-00292-7

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