N4-acetylcytidine-dependent GLMP mRNA stabilization by NAT10 promotes head and neck squamous cell carcinoma metastasis and remodels tumor microenvironment through MAPK/ERK signaling pathway

N4-acetylcytidine (ac4C) is a post-transcriptional RNA modification that regulates in various important biological processes. However, its role in human cancer, especially lymph node metastasis, remains largely unknown. Here, we demonstrated N-Acetyltransferase 10 (NAT10), as the only known “writer”...

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Detalles Bibliográficos
Autores principales: Liu, Yuanyuan, Wang, Xing, Liu, Yuying, Yang, Jianqiang, Mao, Wei, Feng, Chen, Wu, Xiaoliang, Chen, Xinwei, Chen, Lixiao, Dong, Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620198/
https://www.ncbi.nlm.nih.gov/pubmed/37914704
http://dx.doi.org/10.1038/s41419-023-06245-6

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