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Lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images

Traditional Cholangiocarcinoma detection methodology, which involves manual interpretation of histopathological images obtained after biopsy, necessitates extraordinary domain expertise and a significant level of subjectivity, resulting in several deaths due to improper or delayed detection of this...

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Autores principales: Chakrabarti, Shubhadip, Rao, Ummity Srinivasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620203/
https://www.ncbi.nlm.nih.gov/pubmed/37914815
http://dx.doi.org/10.1038/s41598-023-46152-6
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author Chakrabarti, Shubhadip
Rao, Ummity Srinivasa
author_facet Chakrabarti, Shubhadip
Rao, Ummity Srinivasa
author_sort Chakrabarti, Shubhadip
collection PubMed
description Traditional Cholangiocarcinoma detection methodology, which involves manual interpretation of histopathological images obtained after biopsy, necessitates extraordinary domain expertise and a significant level of subjectivity, resulting in several deaths due to improper or delayed detection of this cancer that develops in the bile duct lining. Automation in the diagnosis of this dreadful disease is desperately needed to allow for more effective and faster identification of the disease with a better degree of accuracy and reliability, ultimately saving countless human lives. The primary goal of this study is to develop a machine-assisted method of automation for the accurate and rapid identification of Cholangiocarcinoma utilizing histopathology images with little preprocessing. This work proposes CholangioNet, a novel lightweight neural network for detecting Cholangiocarcinoma utilizing histological RGB images. The histological RGB image dataset considered in this research work was found to have limited number of images, hence data augmentation was performed to increase the number of images. The finally obtained dataset was then subjected to minimal preprocessing procedures. These preprocessed images were then fed into the proposed lightweight CholangioNet. The performance of this proposed architecture is then compared with the performance of some of the prominent existing architectures like, VGG16, VGG19, ResNet50 and ResNet101. The Accuracy, Loss, Precision, and Sensitivity metrics are used to assess the efficiency of the proposed system. At 200 epochs, the proposed architecture achieves maximum training accuracy, precision, and recall of 99.90%, 100%, and 100%, respectively. The suggested architecture's validation accuracy, precision, and recall are 98.40%, 100%, and 100%, respectively. When compared to the performance of other AI-based models, the proposed system produced better results making it a potential AI tool for real world application.
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spelling pubmed-106202032023-11-03 Lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images Chakrabarti, Shubhadip Rao, Ummity Srinivasa Sci Rep Article Traditional Cholangiocarcinoma detection methodology, which involves manual interpretation of histopathological images obtained after biopsy, necessitates extraordinary domain expertise and a significant level of subjectivity, resulting in several deaths due to improper or delayed detection of this cancer that develops in the bile duct lining. Automation in the diagnosis of this dreadful disease is desperately needed to allow for more effective and faster identification of the disease with a better degree of accuracy and reliability, ultimately saving countless human lives. The primary goal of this study is to develop a machine-assisted method of automation for the accurate and rapid identification of Cholangiocarcinoma utilizing histopathology images with little preprocessing. This work proposes CholangioNet, a novel lightweight neural network for detecting Cholangiocarcinoma utilizing histological RGB images. The histological RGB image dataset considered in this research work was found to have limited number of images, hence data augmentation was performed to increase the number of images. The finally obtained dataset was then subjected to minimal preprocessing procedures. These preprocessed images were then fed into the proposed lightweight CholangioNet. The performance of this proposed architecture is then compared with the performance of some of the prominent existing architectures like, VGG16, VGG19, ResNet50 and ResNet101. The Accuracy, Loss, Precision, and Sensitivity metrics are used to assess the efficiency of the proposed system. At 200 epochs, the proposed architecture achieves maximum training accuracy, precision, and recall of 99.90%, 100%, and 100%, respectively. The suggested architecture's validation accuracy, precision, and recall are 98.40%, 100%, and 100%, respectively. When compared to the performance of other AI-based models, the proposed system produced better results making it a potential AI tool for real world application. Nature Publishing Group UK 2023-11-01 /pmc/articles/PMC10620203/ /pubmed/37914815 http://dx.doi.org/10.1038/s41598-023-46152-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Chakrabarti, Shubhadip
Rao, Ummity Srinivasa
Lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images
title Lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images
title_full Lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images
title_fullStr Lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images
title_full_unstemmed Lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images
title_short Lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images
title_sort lightweight neural network for smart diagnosis of cholangiocarcinoma using histopathological images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620203/
https://www.ncbi.nlm.nih.gov/pubmed/37914815
http://dx.doi.org/10.1038/s41598-023-46152-6
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