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Using biologically synthesized TiO(2) nanoparticles as potential remedy against multiple drug resistant Staphylococcus aureus of bovine mastitis

Presently, there is considerable emphasis on biological synthesis of nanoparticles containing bioactive reducing compounds with an aim to mitigate the harmful effects of pollutants. The approach under study is simple and ideal for the production of durable antimicrobial nanomaterials by novel single...

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Autores principales: Ul-Hamid, Anwar, Baig, Nadeem, Haider, Ali, Hakeem, Abbas S., Ikram, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620395/
https://www.ncbi.nlm.nih.gov/pubmed/37914792
http://dx.doi.org/10.1038/s41598-023-45762-4
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author Ul-Hamid, Anwar
Baig, Nadeem
Haider, Ali
Hakeem, Abbas S.
Ikram, Muhammad
author_facet Ul-Hamid, Anwar
Baig, Nadeem
Haider, Ali
Hakeem, Abbas S.
Ikram, Muhammad
author_sort Ul-Hamid, Anwar
collection PubMed
description Presently, there is considerable emphasis on biological synthesis of nanoparticles containing bioactive reducing compounds with an aim to mitigate the harmful effects of pollutants. The approach under study is simple and ideal for the production of durable antimicrobial nanomaterials by novel single-step green synthesis of TiO(2) metal oxide nanostructures using ginger and garlic crude aqueous extracts with bactericidal and catalytic activity. A variety of experimental techniques were used to characterize the synthesized nanomaterials. As demonstrated using x-ray diffraction and ultra-violet visible spectroscopy, the produced nanoparticles exhibited high absorption at 318 nm with size varying between 23.38 nm for ginger and 58.64 nm for garlic in biologically-reduced TiO(2). At increasing concentrations (500, 1000 µg/50 µl), nanoparticles reduced with garlic exhibited enhanced bactericidal efficacy against multiple drug-resistant S. aureus and effectively decomposed toxic methylene blue (MB) dye. In conclusion, biologically-reduced TiO(2) nanoparticles may prove an effective tool in the fight against microbial illnesses and drug resistance.
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spelling pubmed-106203952023-11-03 Using biologically synthesized TiO(2) nanoparticles as potential remedy against multiple drug resistant Staphylococcus aureus of bovine mastitis Ul-Hamid, Anwar Baig, Nadeem Haider, Ali Hakeem, Abbas S. Ikram, Muhammad Sci Rep Article Presently, there is considerable emphasis on biological synthesis of nanoparticles containing bioactive reducing compounds with an aim to mitigate the harmful effects of pollutants. The approach under study is simple and ideal for the production of durable antimicrobial nanomaterials by novel single-step green synthesis of TiO(2) metal oxide nanostructures using ginger and garlic crude aqueous extracts with bactericidal and catalytic activity. A variety of experimental techniques were used to characterize the synthesized nanomaterials. As demonstrated using x-ray diffraction and ultra-violet visible spectroscopy, the produced nanoparticles exhibited high absorption at 318 nm with size varying between 23.38 nm for ginger and 58.64 nm for garlic in biologically-reduced TiO(2). At increasing concentrations (500, 1000 µg/50 µl), nanoparticles reduced with garlic exhibited enhanced bactericidal efficacy against multiple drug-resistant S. aureus and effectively decomposed toxic methylene blue (MB) dye. In conclusion, biologically-reduced TiO(2) nanoparticles may prove an effective tool in the fight against microbial illnesses and drug resistance. Nature Publishing Group UK 2023-11-01 /pmc/articles/PMC10620395/ /pubmed/37914792 http://dx.doi.org/10.1038/s41598-023-45762-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ul-Hamid, Anwar
Baig, Nadeem
Haider, Ali
Hakeem, Abbas S.
Ikram, Muhammad
Using biologically synthesized TiO(2) nanoparticles as potential remedy against multiple drug resistant Staphylococcus aureus of bovine mastitis
title Using biologically synthesized TiO(2) nanoparticles as potential remedy against multiple drug resistant Staphylococcus aureus of bovine mastitis
title_full Using biologically synthesized TiO(2) nanoparticles as potential remedy against multiple drug resistant Staphylococcus aureus of bovine mastitis
title_fullStr Using biologically synthesized TiO(2) nanoparticles as potential remedy against multiple drug resistant Staphylococcus aureus of bovine mastitis
title_full_unstemmed Using biologically synthesized TiO(2) nanoparticles as potential remedy against multiple drug resistant Staphylococcus aureus of bovine mastitis
title_short Using biologically synthesized TiO(2) nanoparticles as potential remedy against multiple drug resistant Staphylococcus aureus of bovine mastitis
title_sort using biologically synthesized tio(2) nanoparticles as potential remedy against multiple drug resistant staphylococcus aureus of bovine mastitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620395/
https://www.ncbi.nlm.nih.gov/pubmed/37914792
http://dx.doi.org/10.1038/s41598-023-45762-4
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