A(2A)R eGFP reporter mouse enables elucidation of A(2A)R expression dynamics during anti-tumor immune responses

There is significant clinical interest in targeting adenosine-mediated immunosuppression, with several small molecule inhibitors having been developed for targeting the A(2A)R receptor. Understanding of the mechanism by which A(2A)R is regulated has been hindered by difficulty in identifying the cel...

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Detalles Bibliográficos
Autores principales: Todd, Kirsten L., Lai, Junyun, Sek, Kevin, Huang, Yu-Kuan, Newman, Dane M., Derrick, Emily B., Koay, Hui-Fern, Nguyen, Dat, Hoang, Thang X., Petley, Emma V., Chan, Cheok Weng, Munoz, Isabelle, House, Imran G., Lee, Joel N., Kim, Joelle S., Li, Jasmine, Tong, Junming, N. de Menezes, Maria, Scheffler, Christina M., Yap, Kah Min, Chen, Amanda X. Y., Dunbar, Phoebe A., Haugen, Brandon, Parish, Ian A., Johnstone, Ricky W., Darcy, Phillip K., Beavis, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620403/
https://www.ncbi.nlm.nih.gov/pubmed/37914685
http://dx.doi.org/10.1038/s41467-023-42734-0

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