Is ongoing testosterone required after pubertal induction in Duchenne muscular dystrophy?

Glucocorticoids (GCs) reduce inflammation and preserve muscle function in boys with Duchenne muscular dystrophy (DMD) but cause pubertal delay. Pubertal induction with testosterone is recommended but longer-term outcome is unknown. OBJECTIVE: To assess hypothalamic–pituitary–gonadal axis, muscle vol...

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Detalles Bibliográficos
Autores principales: Wood, Claire L, Hollingsworth, Kieren G, Bokaie, Edrina, Hughes, Eric, Muni-Lofra, Robert, Mayhew, Anna, Mitchell, Rod T, Guglieri, Michela, McElvaney, Joseph, Cheetham, Timothy D, Straub, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620460/
https://www.ncbi.nlm.nih.gov/pubmed/37768006
http://dx.doi.org/10.1530/EC-23-0245

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