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Asciminib in chronic myeloid leukemia: a STAMP for expedited delivery?

Asciminib is a novel tyrosine kinase inhibitor (TKI) that specifically targets the myristoyl pocket. It has increased selectivity and potent activity against BCR-ABL1 and the mutants that most frequently prevent the activity of the ATP-binding competitive inhibitors. Results for clinical trials in p...

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Detalles Bibliográficos
Autores principales: Padala, Sandeep, Cortes, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620583/
https://www.ncbi.nlm.nih.gov/pubmed/37102603
http://dx.doi.org/10.3324/haematol.2022.282361

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