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Clinical and molecular correlates of somatic and germline DDX41 variants in patients and families with myeloid neoplasms

The diagnosis of germline predisposition to myeloid neoplasms (MN) secondary to DDX41 variants is currently hindered by the long latency period, variable family histories and the frequent occurrence of DDX41 variants of uncertain significance (VUS). We reviewed 4,524 consecutive patients who underwe...

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Detalles Bibliográficos
Autores principales:	Badar, Talha, Nanaa, Ahmad, Foran, James M., Viswanatha, David, Al-Kali, Aref, Lasho, Terra, Finke, Christy, Alkhateeb, Hassan B., He, Rong, Gangat, Naseema, Shah, Mithun, Tefferi, Ayalew, Mangaonkar, Abhishek A., Litzow, Mark R., Ongie, Laura J., Chlon, Timothy, Ferrer, Alejandro, Patnaik, Mrinal M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Fondazione Ferrata Storti 2023
Materias:	Article - Myelodysplastic Syndromes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620593/ https://www.ncbi.nlm.nih.gov/pubmed/37199125 http://dx.doi.org/10.3324/haematol.2023.282867

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