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Design of electron-donating group substituted 2-PAM analogs as antidotes for organophosphate insecticide poisoning

The use of organophosphate (OPs) pesticides is widespread in agriculture and horticulture, but these chemicals can be lethal to humans, causing fatalities and deaths each year. The inhibition of acetylcholinesterase (AChE) by OPs leads to the overstimulation of cholinergic receptors, ultimately resu...

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Detalles Bibliográficos
Autores principales: Kongkaew, Nalinee, Hengphasatporn, Kowit, Injongkol, Yuwanda, Mee-udorn, Pitchayathida, Shi, Liyi, Mahalapbutr, Panupong, Maitarad, Phornphimon, Harada, Ryuhei, Shigeta, Yasuteru, Rungrotmongkol, Thanyada, Vangnai, Alisa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620644/
https://www.ncbi.nlm.nih.gov/pubmed/37928857
http://dx.doi.org/10.1039/d3ra03087c