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Combinatorial blockade for cancer immunotherapy: targeting emerging immune checkpoint receptors
The differentiation, survival, and effector function of tumor-specific CD8(+) cytotoxic T cells lie at the center of antitumor immunity. Due to the lack of proper costimulation and the abundant immunosuppressive mechanisms, tumor-specific T cells show a lack of persistence and exhausted and dysfunct...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620683/ https://www.ncbi.nlm.nih.gov/pubmed/37928556 http://dx.doi.org/10.3389/fimmu.2023.1264327 |