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Dynamic “Cap”‐abilities of P‐bodies and the XRN1‐EDC4 axis
RNA turnover regulates the quality and quantity of cellular gene expression through a coordinated cavalcade of enzymes, factors, and phase transitions. In this issue, Brothers et al reveal the importance of balanced communication between the Xrn1 exonuclease and the EDC4 decapping factor to coordina...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620757/ https://www.ncbi.nlm.nih.gov/pubmed/37750488 http://dx.doi.org/10.15252/embj.2023115310 |
| _version_ | 1785130270459953152 |
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| author | Malsick, Lauren E Wilusz, Jeffrey |
| author_facet | Malsick, Lauren E Wilusz, Jeffrey |
| author_sort | Malsick, Lauren E |
| collection | PubMed |
| description | RNA turnover regulates the quality and quantity of cellular gene expression through a coordinated cavalcade of enzymes, factors, and phase transitions. In this issue, Brothers et al reveal the importance of balanced communication between the Xrn1 exonuclease and the EDC4 decapping factor to coordinate P‐body dynamics and maintain cellular fitness. |
| format | Online Article Text |
| id | pubmed-10620757 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-106207572023-11-03 Dynamic “Cap”‐abilities of P‐bodies and the XRN1‐EDC4 axis Malsick, Lauren E Wilusz, Jeffrey EMBO J News & Views RNA turnover regulates the quality and quantity of cellular gene expression through a coordinated cavalcade of enzymes, factors, and phase transitions. In this issue, Brothers et al reveal the importance of balanced communication between the Xrn1 exonuclease and the EDC4 decapping factor to coordinate P‐body dynamics and maintain cellular fitness. John Wiley and Sons Inc. 2023-09-26 /pmc/articles/PMC10620757/ /pubmed/37750488 http://dx.doi.org/10.15252/embj.2023115310 Text en © 2023 The Authors. Published under the terms of the CC BY NC ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | News & Views Malsick, Lauren E Wilusz, Jeffrey Dynamic “Cap”‐abilities of P‐bodies and the XRN1‐EDC4 axis |
| title | Dynamic “Cap”‐abilities of P‐bodies and the XRN1‐EDC4 axis |
| title_full | Dynamic “Cap”‐abilities of P‐bodies and the XRN1‐EDC4 axis |
| title_fullStr | Dynamic “Cap”‐abilities of P‐bodies and the XRN1‐EDC4 axis |
| title_full_unstemmed | Dynamic “Cap”‐abilities of P‐bodies and the XRN1‐EDC4 axis |
| title_short | Dynamic “Cap”‐abilities of P‐bodies and the XRN1‐EDC4 axis |
| title_sort | dynamic “cap”‐abilities of p‐bodies and the xrn1‐edc4 axis |
| topic | News & Views |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620757/ https://www.ncbi.nlm.nih.gov/pubmed/37750488 http://dx.doi.org/10.15252/embj.2023115310 |
| work_keys_str_mv | AT malsicklaurene dynamiccapabilitiesofpbodiesandthexrn1edc4axis AT wiluszjeffrey dynamiccapabilitiesofpbodiesandthexrn1edc4axis |