Reinvestigation of the Automated Synthesis of Stoichiometrically Conjugated Antibodies to Access High Molecular Weight Payloads and Multiplexed Conjugation via an In-Solution Trans-Tagging Process

Protein conjugates have found applications in a wide variety of fields, ranging from therapeutics to imaging and detection. However, robust control over the parameters of the conjugation process (such as sites and degree of conjugation) remains challenging. Previously, our group introduced Equimolar...

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Detalles Bibliográficos
Autores principales: Lehot, Victor, Lidický, Ondřej, Most, Julien, Erb, Stéphane, Dovgan, Igor, Osypenko, Artem, Koniev, Oleksandr, Kolodych, Sergii, Kotrchová, Lenka, Chaubet, Guilhem, Cianférani, Sarah, Etrych, Tomáš, Wagner, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620776/
https://www.ncbi.nlm.nih.gov/pubmed/37929096
http://dx.doi.org/10.1021/acsomega.3c05206

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