XPOT Disruption Suppresses TNBC Growth through Inhibition of Specific tRNA Nuclear Exportation and TTC19 Expression to Induce Cytokinesis Failure

Transfer RNAs (tRNAs) impact the development and progression of various cancers, but how individual tRNAs are modulated during triple-negative breast cancer (TNBC) progression remains poorly understood. Here, we found that XPOT (Exportin-T), a nuclear export protein receptor of tRNAs, is associated...

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Detalles Bibliográficos
Autores principales: Dai, Huijuan, Yang, Xiaomei, Sheng, Xiaonan, Wang, Yaohui, Zhang, Shan, Zhang, Xueli, Hu, Lipeng, Zhang, Zhigang, Dong, Xinrui, Yin, Wenjin, Yao, Linli, Lu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620816/
https://www.ncbi.nlm.nih.gov/pubmed/37928256
http://dx.doi.org/10.7150/ijbs.85006

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