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Pulmonary Cavitary Sarcoidosis: A Case Report
Sarcoidosis is a granulomatous disease characterized by a non-caseating granuloma formation in different organs of the body. However, the presence of cavitary lesions is rare. We present a case report of a 38-year-old male who presented with a three-month history of cough, dyspnea, and weight loss....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620841/ https://www.ncbi.nlm.nih.gov/pubmed/37927735 http://dx.doi.org/10.7759/cureus.46398 |
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author | Shrestha, Bhanu Mahat, Ravi |
author_facet | Shrestha, Bhanu Mahat, Ravi |
author_sort | Shrestha, Bhanu |
collection | PubMed |
description | Sarcoidosis is a granulomatous disease characterized by a non-caseating granuloma formation in different organs of the body. However, the presence of cavitary lesions is rare. We present a case report of a 38-year-old male who presented with a three-month history of cough, dyspnea, and weight loss. Computed tomography of the chest demonstrated enlarged mediastinal and bilateral hilar lymphadenopathy with bilateral perihilar consolidation and cavitation in the upper lobes of both lungs. Later, the patient underwent bronchoscopy with bronchoalveolar lavage and endobronchial biopsy which showed well-formed and non-necrotizing granulomas which were also embedded in the dense hyaline sclerosis. This finding is consistent with sarcoidosis. Treatment with systemic corticosteroids was initiated, resulting in significant improvement in the patient’s symptoms. This case report highlights the uncommon manifestation of pulmonary cavitary sarcoidosis and emphasizes the significance of accurate diagnosis and appropriate management of this complex disease. |
format | Online Article Text |
id | pubmed-10620841 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-106208412023-11-03 Pulmonary Cavitary Sarcoidosis: A Case Report Shrestha, Bhanu Mahat, Ravi Cureus Pathology Sarcoidosis is a granulomatous disease characterized by a non-caseating granuloma formation in different organs of the body. However, the presence of cavitary lesions is rare. We present a case report of a 38-year-old male who presented with a three-month history of cough, dyspnea, and weight loss. Computed tomography of the chest demonstrated enlarged mediastinal and bilateral hilar lymphadenopathy with bilateral perihilar consolidation and cavitation in the upper lobes of both lungs. Later, the patient underwent bronchoscopy with bronchoalveolar lavage and endobronchial biopsy which showed well-formed and non-necrotizing granulomas which were also embedded in the dense hyaline sclerosis. This finding is consistent with sarcoidosis. Treatment with systemic corticosteroids was initiated, resulting in significant improvement in the patient’s symptoms. This case report highlights the uncommon manifestation of pulmonary cavitary sarcoidosis and emphasizes the significance of accurate diagnosis and appropriate management of this complex disease. Cureus 2023-10-03 /pmc/articles/PMC10620841/ /pubmed/37927735 http://dx.doi.org/10.7759/cureus.46398 Text en Copyright © 2023, Shrestha et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Shrestha, Bhanu Mahat, Ravi Pulmonary Cavitary Sarcoidosis: A Case Report |
title | Pulmonary Cavitary Sarcoidosis: A Case Report |
title_full | Pulmonary Cavitary Sarcoidosis: A Case Report |
title_fullStr | Pulmonary Cavitary Sarcoidosis: A Case Report |
title_full_unstemmed | Pulmonary Cavitary Sarcoidosis: A Case Report |
title_short | Pulmonary Cavitary Sarcoidosis: A Case Report |
title_sort | pulmonary cavitary sarcoidosis: a case report |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620841/ https://www.ncbi.nlm.nih.gov/pubmed/37927735 http://dx.doi.org/10.7759/cureus.46398 |
work_keys_str_mv | AT shresthabhanu pulmonarycavitarysarcoidosisacasereport AT mahatravi pulmonarycavitarysarcoidosisacasereport |