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Pulmonary Cavitary Sarcoidosis: A Case Report

Sarcoidosis is a granulomatous disease characterized by a non-caseating granuloma formation in different organs of the body. However, the presence of cavitary lesions is rare. We present a case report of a 38-year-old male who presented with a three-month history of cough, dyspnea, and weight loss....

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Detalles Bibliográficos
Autores principales: Shrestha, Bhanu, Mahat, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620841/
https://www.ncbi.nlm.nih.gov/pubmed/37927735
http://dx.doi.org/10.7759/cureus.46398
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author Shrestha, Bhanu
Mahat, Ravi
author_facet Shrestha, Bhanu
Mahat, Ravi
author_sort Shrestha, Bhanu
collection PubMed
description Sarcoidosis is a granulomatous disease characterized by a non-caseating granuloma formation in different organs of the body. However, the presence of cavitary lesions is rare. We present a case report of a 38-year-old male who presented with a three-month history of cough, dyspnea, and weight loss. Computed tomography of the chest demonstrated enlarged mediastinal and bilateral hilar lymphadenopathy with bilateral perihilar consolidation and cavitation in the upper lobes of both lungs. Later, the patient underwent bronchoscopy with bronchoalveolar lavage and endobronchial biopsy which showed well-formed and non-necrotizing granulomas which were also embedded in the dense hyaline sclerosis. This finding is consistent with sarcoidosis. Treatment with systemic corticosteroids was initiated, resulting in significant improvement in the patient’s symptoms. This case report highlights the uncommon manifestation of pulmonary cavitary sarcoidosis and emphasizes the significance of accurate diagnosis and appropriate management of this complex disease.
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spelling pubmed-106208412023-11-03 Pulmonary Cavitary Sarcoidosis: A Case Report Shrestha, Bhanu Mahat, Ravi Cureus Pathology Sarcoidosis is a granulomatous disease characterized by a non-caseating granuloma formation in different organs of the body. However, the presence of cavitary lesions is rare. We present a case report of a 38-year-old male who presented with a three-month history of cough, dyspnea, and weight loss. Computed tomography of the chest demonstrated enlarged mediastinal and bilateral hilar lymphadenopathy with bilateral perihilar consolidation and cavitation in the upper lobes of both lungs. Later, the patient underwent bronchoscopy with bronchoalveolar lavage and endobronchial biopsy which showed well-formed and non-necrotizing granulomas which were also embedded in the dense hyaline sclerosis. This finding is consistent with sarcoidosis. Treatment with systemic corticosteroids was initiated, resulting in significant improvement in the patient’s symptoms. This case report highlights the uncommon manifestation of pulmonary cavitary sarcoidosis and emphasizes the significance of accurate diagnosis and appropriate management of this complex disease. Cureus 2023-10-03 /pmc/articles/PMC10620841/ /pubmed/37927735 http://dx.doi.org/10.7759/cureus.46398 Text en Copyright © 2023, Shrestha et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Shrestha, Bhanu
Mahat, Ravi
Pulmonary Cavitary Sarcoidosis: A Case Report
title Pulmonary Cavitary Sarcoidosis: A Case Report
title_full Pulmonary Cavitary Sarcoidosis: A Case Report
title_fullStr Pulmonary Cavitary Sarcoidosis: A Case Report
title_full_unstemmed Pulmonary Cavitary Sarcoidosis: A Case Report
title_short Pulmonary Cavitary Sarcoidosis: A Case Report
title_sort pulmonary cavitary sarcoidosis: a case report
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620841/
https://www.ncbi.nlm.nih.gov/pubmed/37927735
http://dx.doi.org/10.7759/cureus.46398
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