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Predicting active enhancers with DNA methylation and histone modification

BACKGROUND: Enhancers play a crucial role in gene regulation, and some active enhancers produce noncoding RNAs known as enhancer RNAs (eRNAs) bi-directionally. The most commonly used method for detecting eRNAs is CAGE-seq, but the instability of eRNAs in vivo leads to data noise in sequencing result...

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Detalles Bibliográficos
Autores principales: Luo, Ximei, Li, Qun, Tang, Yifan, Liu, Yan, Zou, Quan, Zheng, Jie, Zhang, Ying, Xu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621108/
https://www.ncbi.nlm.nih.gov/pubmed/37919681
http://dx.doi.org/10.1186/s12859-023-05547-y

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