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Predicting active enhancers with DNA methylation and histone modification
BACKGROUND: Enhancers play a crucial role in gene regulation, and some active enhancers produce noncoding RNAs known as enhancer RNAs (eRNAs) bi-directionally. The most commonly used method for detecting eRNAs is CAGE-seq, but the instability of eRNAs in vivo leads to data noise in sequencing result...
Autores principales: | Luo, Ximei, Li, Qun, Tang, Yifan, Liu, Yan, Zou, Quan, Zheng, Jie, Zhang, Ying, Xu, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621108/ https://www.ncbi.nlm.nih.gov/pubmed/37919681 http://dx.doi.org/10.1186/s12859-023-05547-y |
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