The TFPI2–PPARγ axis induces M2 polarization and inhibits fibroblast activation to promote recovery from post-myocardial infarction in diabetic mice

BACKGROUND: Diabetes mellitus is one of the causes of poor ventricular remodelling and poor cardiac recovery after myocardial infarction (MI). We previously reported that tissue factor pathway inhibitor-2 (TFPI2) was downregulated in response to hyperglycaemia and that it played a pivotal role in ex...

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Detalles Bibliográficos
Autores principales: Guo, Mengqi, Xia, Zongyi, Hong, Yefeng, Ji, Hongwei, Li, Fuhai, Liu, Wenheng, Li, Shaohua, Xin, Hui, Tan, Kai, Lian, Zhexun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621166/
https://www.ncbi.nlm.nih.gov/pubmed/37915070
http://dx.doi.org/10.1186/s12950-023-00357-8

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