Soluble epoxide hydrolase deficiency attenuates airway inflammation in COPD via IRE1α/JNK/AP-1 signaling pathway

BACKGROUND: Soluble Epoxide Hydrolase (sEH) metabolizes anti-inflammatory epoxyeicosatrienoic acids and critically affects airway inflammation in chronic obstructive pulmonary disease (COPD). Considering the excessive endoplasmic reticulum stress is associated with the earlier onset of COPD. The rol...

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Detalles Bibliográficos
Autores principales: Yu, Yue, Yang, Ailin, He, Xin, Wu, Bo, Wu, Yanjun, Li, Yunxiao, Nie, Shan, Xu, Bo, Wang, Haoyan, Yu, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621191/
https://www.ncbi.nlm.nih.gov/pubmed/37915073
http://dx.doi.org/10.1186/s12950-023-00361-y

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