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Anti-proliferative activity of RIHMS-Qi-23 against MCF-7 breast cancer cell line is through inhibition of cell proliferation and senescence but not inhibition of targeted kinases

BACKGROUND: Breast cancer is the most common malignancy globally, and is considered a major cause of cancer-related death. Tremendous effort is exerted to identify an optimal anticancer drug with limited side effects. The quinoline derivative RIMHS-Qi-23 had a wide-spectrum antiproliferative activit...

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Detalles Bibliográficos
Autores principales: El-Gamal, Randa, Elfarrash, Sara, EL-Nablaway, Mohammad, Salem, Asmaa Ahmed, Zaraei, Seyed-Omar, Anbar, Hanan S., Shoma, Ashraf, El-Gamal, Mohammed I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621201/
https://www.ncbi.nlm.nih.gov/pubmed/37919708
http://dx.doi.org/10.1186/s12885-023-11547-1