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Lactate is a bridge linking glycolysis and autophagy through lactylation
Lactate is a glycolysis product that is produced from pyruvate by LDH (lactate dehydrogenase) and plays an important role in physiological and pathological processes. However, whether lactate regulates autophagy is still unknown. We recently reported that LDHA is phosphorylated at serine 196 by ULK1...
Autores principales: | Sun, Weixia, Jia, Mengshu, Feng, Yingyan, Cheng, Xiawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621282/ https://www.ncbi.nlm.nih.gov/pubmed/37565742 http://dx.doi.org/10.1080/15548627.2023.2246356 |
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