Production of a p65(fl/fl)/LysMCre mouse model with dysfunctional NF-κB signaling in bone marrow-derived macrophages

Here, we describe the production and characterization of a novel p65(fl/fl)/LysMCre mouse model, which lacks canonical nuclear factor-kappaB member RelA/p65 (indicated as p65 hereafter) in bone marrow-derived macrophages. Cultured bone marrow-derived macrophages that lack p65 protein reveal NF-κB si...

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Detalles Bibliográficos
Autores principales: Korkaya, Ahmet K., Fischer, Jeffrey, Peppers, Anthony, Crosson, Sean M., Rayamajhi, Manira, Miao, Edward A., Baldwin, Albert S., Bradford, Jennifer W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621469/
https://www.ncbi.nlm.nih.gov/pubmed/37828842
http://dx.doi.org/10.1177/17534259231205993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621469/
https://www.ncbi.nlm.nih.gov/pubmed/37828842
http://dx.doi.org/10.1177/17534259231205993

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