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Production of a p65(fl/fl)/LysMCre mouse model with dysfunctional NF-κB signaling in bone marrow-derived macrophages
Here, we describe the production and characterization of a novel p65(fl/fl)/LysMCre mouse model, which lacks canonical nuclear factor-kappaB member RelA/p65 (indicated as p65 hereafter) in bone marrow-derived macrophages. Cultured bone marrow-derived macrophages that lack p65 protein reveal NF-κB si...
Autores principales: | Korkaya, Ahmet K., Fischer, Jeffrey, Peppers, Anthony, Crosson, Sean M., Rayamajhi, Manira, Miao, Edward A., Baldwin, Albert S., Bradford, Jennifer W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10621469/ https://www.ncbi.nlm.nih.gov/pubmed/37828842 http://dx.doi.org/10.1177/17534259231205993 |
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