De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness

Invariant natural-killer T (iNKT) cells play pathogenic roles in allergic asthma in murine models and possibly also humans. While many studies show that the development and functions of innate and adaptive immune cells depend on their metabolic state, the evidence for this in iNKT cells is very limi...

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Detalles Bibliográficos
Autores principales: Koh, Jaemoon, Woo, Yeon Duk, Yoo, Hyun Jung, Choi, Jun-Pyo, Kim, Sae Hoon, Chang, Yoon-Seok, Jung, Kyeong Cheon, Kim, Ji Hyung, Jeon, Yoon Kyung, Kim, Hye Young, Chung, Doo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622147/
https://www.ncbi.nlm.nih.gov/pubmed/37917548
http://dx.doi.org/10.7554/eLife.87536

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