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An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor

INTRODUCTION: Large cell calcifying Sertoli cell tumors are exceedingly rare. They are most commonly benign, but risks for malignancy include older age, larger size of tumor, and solitary tumors. To the author's knowledge, this is the first case reported of an incidental large cell calcifying S...

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Autores principales: Crone, Lauren, Prendergast, Sophie C, Mayer, Nick, O'Brien, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622192/
https://www.ncbi.nlm.nih.gov/pubmed/37928287
http://dx.doi.org/10.1002/iju5.12626
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author Crone, Lauren
Prendergast, Sophie C
Mayer, Nick
O'Brien, Frank
author_facet Crone, Lauren
Prendergast, Sophie C
Mayer, Nick
O'Brien, Frank
author_sort Crone, Lauren
collection PubMed
description INTRODUCTION: Large cell calcifying Sertoli cell tumors are exceedingly rare. They are most commonly benign, but risks for malignancy include older age, larger size of tumor, and solitary tumors. To the author's knowledge, this is the first case reported of an incidental large cell calcifying Sertoli cell tumor when an orchidectomy was performed for a separate lesion. CASE PRESENTATION: A 31‐year‐old male presented with a painless testicular lump. Ultrasound demonstrated an exophytic lesion in the superolateral aspect and calcifications were noted inferomedially and inferolaterally in the right testis. On histology from radical orchidectomy, the superolateral lesion was found to be an adenomatoid tumor, and the calcifications inferiorly represented a large cell calcifying Sertoli cell tumor. The background showed foci of germ cell neoplasia in situ but no evidence of invasive malignancy. CONCLUSION: Calcifications on ultrasound in isolation may represent large cell calcifying Sertoli Cell tumors.
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spelling pubmed-106221922023-11-03 An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor Crone, Lauren Prendergast, Sophie C Mayer, Nick O'Brien, Frank IJU Case Rep Case Reports INTRODUCTION: Large cell calcifying Sertoli cell tumors are exceedingly rare. They are most commonly benign, but risks for malignancy include older age, larger size of tumor, and solitary tumors. To the author's knowledge, this is the first case reported of an incidental large cell calcifying Sertoli cell tumor when an orchidectomy was performed for a separate lesion. CASE PRESENTATION: A 31‐year‐old male presented with a painless testicular lump. Ultrasound demonstrated an exophytic lesion in the superolateral aspect and calcifications were noted inferomedially and inferolaterally in the right testis. On histology from radical orchidectomy, the superolateral lesion was found to be an adenomatoid tumor, and the calcifications inferiorly represented a large cell calcifying Sertoli cell tumor. The background showed foci of germ cell neoplasia in situ but no evidence of invasive malignancy. CONCLUSION: Calcifications on ultrasound in isolation may represent large cell calcifying Sertoli Cell tumors. John Wiley and Sons Inc. 2023-09-20 /pmc/articles/PMC10622192/ /pubmed/37928287 http://dx.doi.org/10.1002/iju5.12626 Text en © 2023 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Crone, Lauren
Prendergast, Sophie C
Mayer, Nick
O'Brien, Frank
An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor
title An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor
title_full An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor
title_fullStr An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor
title_full_unstemmed An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor
title_short An incidental finding of large cell calcifying Sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor
title_sort incidental finding of large cell calcifying sertoli cell tumor in an orchidectomy specimen for a separate adenomatoid tumor
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622192/
https://www.ncbi.nlm.nih.gov/pubmed/37928287
http://dx.doi.org/10.1002/iju5.12626
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