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Local application of engineered insulin-like growth factor I mRNA demonstrates regenerative therapeutic potential in vivo

Insulin-like growth factor I (IGF-I) is a growth-promoting anabolic hormone that fosters cell growth and tissue homeostasis. IGF-I deficiency is associated with several diseases, including growth disorders and neurological and musculoskeletal diseases due to impaired regeneration. Despite the vast r...

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Detalles Bibliográficos
Autores principales: Antony, Justin S., Birrer, Pascale, Bohnert, Claudia, Zimmerli, Sina, Hillmann, Petra, Schaffhauser, Hervé, Hoeflich, Christine, Hoeflich, Andreas, Khairallah, Ramzi, Satoh, Andreas T., Kappeler, Isabelle, Ferreira, Isabel, Zuideveld, Klaas P., Metzger, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622308/
https://www.ncbi.nlm.nih.gov/pubmed/37928443
http://dx.doi.org/10.1016/j.omtn.2023.102055