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Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma
Molecular subtyping of lung squamous cell carcinoma (LUSC) has been performed at the genomic, transcriptomic, and proteomic level. However, LUSC stratification based on tissue metabolomics is still lacking. Combining high-mass-resolution imaging mass spectrometry with consensus clustering, four tumo...
Autores principales: | Wang, Jun, Sun, Na, Kunzke, Thomas, Shen, Jian, Zens, Philipp, Prade, Verena M., Feuchtinger, Annette, Berezowska, Sabina, Walch, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622419/ https://www.ncbi.nlm.nih.gov/pubmed/37919427 http://dx.doi.org/10.1038/s41698-023-00434-4 |
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