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Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma

Molecular subtyping of lung squamous cell carcinoma (LUSC) has been performed at the genomic, transcriptomic, and proteomic level. However, LUSC stratification based on tissue metabolomics is still lacking. Combining high-mass-resolution imaging mass spectrometry with consensus clustering, four tumo...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Sun, Na, Kunzke, Thomas, Shen, Jian, Zens, Philipp, Prade, Verena M., Feuchtinger, Annette, Berezowska, Sabina, Walch, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622419/
https://www.ncbi.nlm.nih.gov/pubmed/37919427
http://dx.doi.org/10.1038/s41698-023-00434-4

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