MAP kinase ERK5 modulates cancer cell sensitivity to extrinsic apoptosis induced by death-receptor agonists

Death receptor ligand TRAIL is a promising cancer therapy due to its ability to selectively trigger extrinsic apoptosis in cancer cells. However, TRAIL–based therapies in humans have shown limitations, mainly due inherent or acquired resistance of tumor cells. To address this issue, current efforts...

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Detalles Bibliográficos
Autores principales: Espinosa-Gil, Sergio, Ivanova, Saska, Alari-Pahissa, Elisenda, Denizli, Melek, Villafranca-Magdalena, Beatriz, Viñas-Casas, Maria, Bolinaga-Ayala, Idoia, Gámez-García, Andrés, Faundez-Vidiella, Claudia, Colas, Eva, Lopez-Botet, Miguel, Zorzano, Antonio, Lizcano, José Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622508/
https://www.ncbi.nlm.nih.gov/pubmed/37919293
http://dx.doi.org/10.1038/s41419-023-06229-6

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