Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics

Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of preci...

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Autores principales: Park, Young Min, Lin, De-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622517/
https://www.ncbi.nlm.nih.gov/pubmed/37919364
http://dx.doi.org/10.1038/s41467-023-42960-6
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author Park, Young Min
Lin, De-Chen
author_facet Park, Young Min
Lin, De-Chen
author_sort Park, Young Min
collection PubMed
description Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.
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spelling pubmed-106225172023-11-04 Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics Park, Young Min Lin, De-Chen Nat Commun Comment Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies. Nature Publishing Group UK 2023-11-02 /pmc/articles/PMC10622517/ /pubmed/37919364 http://dx.doi.org/10.1038/s41467-023-42960-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Park, Young Min
Lin, De-Chen
Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
title Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
title_full Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
title_fullStr Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
title_full_unstemmed Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
title_short Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
title_sort moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622517/
https://www.ncbi.nlm.nih.gov/pubmed/37919364
http://dx.doi.org/10.1038/s41467-023-42960-6
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