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Doxorubicin-induced modulation of TGF-β signaling cascade in mouse fibroblasts: insights into cardiotoxicity mechanisms

Doxorubicin (DOX)-induced cardiotoxicity has been widely observed, yet the specific impact on cardiac fibroblasts is not fully understood. Additionally, the modulation of the transforming growth factor beta (TGF-β) signaling pathway by DOX remains to be fully elucidated. This study investigated DOX’...

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Detalles Bibliográficos
Autores principales: Patricelli, Conner, Lehmann, Parker, Oxford, Julia Thom, Pu, Xinzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622533/
https://www.ncbi.nlm.nih.gov/pubmed/37919370
http://dx.doi.org/10.1038/s41598-023-46216-7