On the origin of the low immunogenicity and biosafety of a neutral α-helical polypeptide as an alternative to polyethylene glycol

Poly(ethylene glycol) (PEG) is a prominent synthetic polymer widely used in biomedicine. Despite its notable success, recent clinical evidence highlights concerns regarding the immunogenicity and adverse effects associated with PEG in PEGylated proteins and lipid nanoparticles. Previous studies have...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jialing, Chen, Junyi, Sun, Yiming, Hou, Yingqin, Liu, Zhibo, Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622589/
https://www.ncbi.nlm.nih.gov/pubmed/37927900
http://dx.doi.org/10.1016/j.bioactmat.2023.10.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622589/
https://www.ncbi.nlm.nih.gov/pubmed/37927900
http://dx.doi.org/10.1016/j.bioactmat.2023.10.011

Ejemplares similares