Broad-spectrum activity of bulevirtide against clinical isolates of HDV and recombinant pan-genotypic combinations of HBV/HDV

BACKGROUND & AIMS: Bulevirtide (BLV) is a small lipopeptide agent that specifically binds to the sodium taurocholate cotransporting polypeptide (NTCP) bile salt transporter and HBV/HDV receptor on the surface of human hepatocytes and inhibits HDV and HBV entry. As a satellite virus of HBV, HDV v...

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Detalles Bibliográficos
Autores principales: Mateo, Roberto, Xu, Simin, Shornikov, Alex, Yazdi, Tahmineh, Liu, Yang, May, Lindsey, Han, Bin, Han, Dong, Martin, Ross, Manhas, Savrina, Richards, Christopher, Marceau, Caleb, Aeschbacher, Thomas, Chang, Silvia, Manuilov, Dmitry, Hollnberger, Julius, Urban, Stephan, Asselah, Tarik, Abdurakhmanov, Dzhamal, Lampertico, Pietro, Maiorova, Evguenia, Mo, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622701/
https://www.ncbi.nlm.nih.gov/pubmed/37929228
http://dx.doi.org/10.1016/j.jhepr.2023.100893

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