Amino-terminal proteolytic fragment of the axon growth inhibitor Nogo-A (Rtn4A) is upregulated by injury and promotes axon regeneration

After adult mammalian central nervous system injury, axon regeneration is extremely limited or absent, resulting in persistent neurological deficits. Axon regeneration failure is due in part to the presence of inhibitory proteins, including NogoA (Rtn4A), from which two inhibitory domains have been...

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Detalles Bibliográficos
Autores principales: Sekine, Yuichi, Wang, Xingxing, Kikkawa, Kazuna, Honda, Sachie, Strittmatter, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622843/
https://www.ncbi.nlm.nih.gov/pubmed/37690690
http://dx.doi.org/10.1016/j.jbc.2023.105232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622843/
https://www.ncbi.nlm.nih.gov/pubmed/37690690
http://dx.doi.org/10.1016/j.jbc.2023.105232

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