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300-fold higher neuro- and immunotoxicity from low-redox transformation of carbamazepine

Current challenges in (eco)toxicology are in understanding the transformation of (reactive) substances, and how transformation affects toxic modes of action. Empirical assessment of transformation products of, practically an infinite number of substances, via experimentation, is impossible. Predicti...

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Detalles Bibliográficos
Autor principal: Nolte, Tom M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622881/
https://www.ncbi.nlm.nih.gov/pubmed/37927955
http://dx.doi.org/10.1016/j.toxrep.2023.09.013