Misregulation of mitochondria–lysosome contact dynamics in Charcot–Marie–Tooth Type 2B disease Rab7 mutant sensory peripheral neurons

Inter-organelle contact sites between mitochondria and lysosomes mediate the crosstalk and bidirectional regulation of their dynamics in health and disease. However, mitochondria–lysosome contact sites and their misregulation have not been investigated in peripheral sensory neurons. Charcot–Marie–To...

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Detalles Bibliográficos
Autores principales: Wong, Yvette C., Jayaraj, Nirupa D., Belton, Tayler B., Shum, George C., Ball, Hannah E., Ren, Dongjun, Tadenev, Abigail L. D., Krainc, Dimitri, Burgess, Robert W., Menichella, Daniela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622892/
https://www.ncbi.nlm.nih.gov/pubmed/37878717
http://dx.doi.org/10.1073/pnas.2313010120

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