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Case Report: Treatment of the rare B-cell lymphoblastic lymphoma with scalp lesion using rotation flap

INTRODUCTION: Leukemia is the most frequently occurring cancer in children, and lymphoblastic lymphoma (LBL) is a rare subtype. LBL are lymphoid neoplasms of B or T cell origin and are primarily treated with chemotherapy. Although cure rates among children are excellent, these patients must be monit...

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Autores principales: Kim, Timothy, Jung, Geena, Buckner-Wolfson, Emery, Fatemi, Ryan, Liriano, Genesis, Tal, Adit, Wang, Yanhua, Tepper, Oren, Kobets, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623147/
https://www.ncbi.nlm.nih.gov/pubmed/37927459
http://dx.doi.org/10.3389/fonc.2023.1252512
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author Kim, Timothy
Jung, Geena
Buckner-Wolfson, Emery
Fatemi, Ryan
Liriano, Genesis
Tal, Adit
Wang, Yanhua
Tepper, Oren
Kobets, Andrew
author_facet Kim, Timothy
Jung, Geena
Buckner-Wolfson, Emery
Fatemi, Ryan
Liriano, Genesis
Tal, Adit
Wang, Yanhua
Tepper, Oren
Kobets, Andrew
author_sort Kim, Timothy
collection PubMed
description INTRODUCTION: Leukemia is the most frequently occurring cancer in children, and lymphoblastic lymphoma (LBL) is a rare subtype. LBL are lymphoid neoplasms of B or T cell origin and are primarily treated with chemotherapy. Although cure rates among children are excellent, these patients must be monitored for relapse. Cutaneous lesions involving B-cell LBL (B-LBL) are extremely rare and here we present a patient with a worsening B-LBL scalp mass who required radical surgical excision. CASE REPORT: A 6-year-old female patient with a history of a nontender scalp mass discovered at approximately 2-3 years of age was evaluated for resection of the nodule due to its size and treatment history. The patient was originally diagnosed with follicular lymphoma by punch biopsy; excision was successfully performed on this 4 cm lesion and upon examination of the skin biopsy did we get a diagnosis of B-LBL. Reconstruction of the scalp was done through the rotation flap method. The patient’s scalp healed well, and adjuvant chemotherapy was continued. There has been no reoccurrence. DISCUSSION: Here we report the rarity of B-LBL cases involving extranodal involvement in the scalp. The most common reconstruction of scalp lesions has been using free flap from the anterolateral thigh (ALT) and latissimus dorsi (LD). Our case used the rotation flap, which has its functional and cosmetic benefits. The importance of monitoring this patient is emphasized due to the dangerous consequences of B-LBL relapse. Ultimately, our successful treatment and care of this rare case can be used as guidance for similar patients in the future.
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spelling pubmed-106231472023-11-04 Case Report: Treatment of the rare B-cell lymphoblastic lymphoma with scalp lesion using rotation flap Kim, Timothy Jung, Geena Buckner-Wolfson, Emery Fatemi, Ryan Liriano, Genesis Tal, Adit Wang, Yanhua Tepper, Oren Kobets, Andrew Front Oncol Oncology INTRODUCTION: Leukemia is the most frequently occurring cancer in children, and lymphoblastic lymphoma (LBL) is a rare subtype. LBL are lymphoid neoplasms of B or T cell origin and are primarily treated with chemotherapy. Although cure rates among children are excellent, these patients must be monitored for relapse. Cutaneous lesions involving B-cell LBL (B-LBL) are extremely rare and here we present a patient with a worsening B-LBL scalp mass who required radical surgical excision. CASE REPORT: A 6-year-old female patient with a history of a nontender scalp mass discovered at approximately 2-3 years of age was evaluated for resection of the nodule due to its size and treatment history. The patient was originally diagnosed with follicular lymphoma by punch biopsy; excision was successfully performed on this 4 cm lesion and upon examination of the skin biopsy did we get a diagnosis of B-LBL. Reconstruction of the scalp was done through the rotation flap method. The patient’s scalp healed well, and adjuvant chemotherapy was continued. There has been no reoccurrence. DISCUSSION: Here we report the rarity of B-LBL cases involving extranodal involvement in the scalp. The most common reconstruction of scalp lesions has been using free flap from the anterolateral thigh (ALT) and latissimus dorsi (LD). Our case used the rotation flap, which has its functional and cosmetic benefits. The importance of monitoring this patient is emphasized due to the dangerous consequences of B-LBL relapse. Ultimately, our successful treatment and care of this rare case can be used as guidance for similar patients in the future. Frontiers Media S.A. 2023-10-20 /pmc/articles/PMC10623147/ /pubmed/37927459 http://dx.doi.org/10.3389/fonc.2023.1252512 Text en Copyright © 2023 Kim, Jung, Buckner-Wolfson, Fatemi, Liriano, Tal, Wang, Tepper and Kobets https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Kim, Timothy
Jung, Geena
Buckner-Wolfson, Emery
Fatemi, Ryan
Liriano, Genesis
Tal, Adit
Wang, Yanhua
Tepper, Oren
Kobets, Andrew
Case Report: Treatment of the rare B-cell lymphoblastic lymphoma with scalp lesion using rotation flap
title Case Report: Treatment of the rare B-cell lymphoblastic lymphoma with scalp lesion using rotation flap
title_full Case Report: Treatment of the rare B-cell lymphoblastic lymphoma with scalp lesion using rotation flap
title_fullStr Case Report: Treatment of the rare B-cell lymphoblastic lymphoma with scalp lesion using rotation flap
title_full_unstemmed Case Report: Treatment of the rare B-cell lymphoblastic lymphoma with scalp lesion using rotation flap
title_short Case Report: Treatment of the rare B-cell lymphoblastic lymphoma with scalp lesion using rotation flap
title_sort case report: treatment of the rare b-cell lymphoblastic lymphoma with scalp lesion using rotation flap
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623147/
https://www.ncbi.nlm.nih.gov/pubmed/37927459
http://dx.doi.org/10.3389/fonc.2023.1252512
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