Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus

Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represe...

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Detalles Bibliográficos
Autores principales: Djokovic, Aleksandra, Krljanac, Gordana, Matic, Predrag, Zivic, Rastko, Djulejic, Vuk, Marjanovic Haljilji, Marija, Popovic, Dusan, Filipovic, Branka, Apostolovic, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623160/
https://www.ncbi.nlm.nih.gov/pubmed/37928766
http://dx.doi.org/10.3389/fcvm.2023.1260478
Descripción
Sumario:Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represents a major clinical challenge. Certain arteriopathies and triggers are related to SCAD, with high variability in their prevalence, and often, the cause remains unknown. The objective of this review is to provide contemporary knowledge of the pathophysiology of SCAD and possible therapeutic solutions.

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