Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus

Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represe...

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Autores principales: Djokovic, Aleksandra, Krljanac, Gordana, Matic, Predrag, Zivic, Rastko, Djulejic, Vuk, Marjanovic Haljilji, Marija, Popovic, Dusan, Filipovic, Branka, Apostolovic, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623160/
https://www.ncbi.nlm.nih.gov/pubmed/37928766
http://dx.doi.org/10.3389/fcvm.2023.1260478
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author Djokovic, Aleksandra
Krljanac, Gordana
Matic, Predrag
Zivic, Rastko
Djulejic, Vuk
Marjanovic Haljilji, Marija
Popovic, Dusan
Filipovic, Branka
Apostolovic, Svetlana
author_facet Djokovic, Aleksandra
Krljanac, Gordana
Matic, Predrag
Zivic, Rastko
Djulejic, Vuk
Marjanovic Haljilji, Marija
Popovic, Dusan
Filipovic, Branka
Apostolovic, Svetlana
author_sort Djokovic, Aleksandra
collection PubMed
description Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represents a major clinical challenge. Certain arteriopathies and triggers are related to SCAD, with high variability in their prevalence, and often, the cause remains unknown. The objective of this review is to provide contemporary knowledge of the pathophysiology of SCAD and possible therapeutic solutions.
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spelling pubmed-106231602023-11-04 Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus Djokovic, Aleksandra Krljanac, Gordana Matic, Predrag Zivic, Rastko Djulejic, Vuk Marjanovic Haljilji, Marija Popovic, Dusan Filipovic, Branka Apostolovic, Svetlana Front Cardiovasc Med Cardiovascular Medicine Spontaneous coronary artery dissection (SCAD) accounts for 1.7%–4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represents a major clinical challenge. Certain arteriopathies and triggers are related to SCAD, with high variability in their prevalence, and often, the cause remains unknown. The objective of this review is to provide contemporary knowledge of the pathophysiology of SCAD and possible therapeutic solutions. Frontiers Media S.A. 2023-10-20 /pmc/articles/PMC10623160/ /pubmed/37928766 http://dx.doi.org/10.3389/fcvm.2023.1260478 Text en © 2023 Djokovic, Krljanac, Matic, Zivic, Djulejic, Marjanovic Haljilji, Popovic, Filipovic and Apostolovic. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Djokovic, Aleksandra
Krljanac, Gordana
Matic, Predrag
Zivic, Rastko
Djulejic, Vuk
Marjanovic Haljilji, Marija
Popovic, Dusan
Filipovic, Branka
Apostolovic, Svetlana
Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus
title Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus
title_full Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus
title_fullStr Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus
title_full_unstemmed Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus
title_short Pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus
title_sort pathophysiology of spontaneous coronary artery dissection: hematoma, not thrombus
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623160/
https://www.ncbi.nlm.nih.gov/pubmed/37928766
http://dx.doi.org/10.3389/fcvm.2023.1260478
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