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Respiratory Epithelial Adenomatoid Hamartoma in a Young Female: A Diagnostic Dilemma

Hamartomas are non-neoplastic tissue abnormalities commonly found in various organs but rarely in the upper aerodigestive tract. Respiratory epithelial adenomatoid hamartoma (REAH) is a rare benign proliferation affecting the nasal cavity and sinonasal tract. It often mimics other nasal masses, lead...

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Autores principales: Mujeeb, Abdul, Singavarapu, Prathap Reddy, Chaganti, Lalitha Alekhya, Seelamonthula, Abhishek Sai, Kotha, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623200/
https://www.ncbi.nlm.nih.gov/pubmed/37927721
http://dx.doi.org/10.7759/cureus.46453
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author Mujeeb, Abdul
Singavarapu, Prathap Reddy
Chaganti, Lalitha Alekhya
Seelamonthula, Abhishek Sai
Kotha, Rakesh
author_facet Mujeeb, Abdul
Singavarapu, Prathap Reddy
Chaganti, Lalitha Alekhya
Seelamonthula, Abhishek Sai
Kotha, Rakesh
author_sort Mujeeb, Abdul
collection PubMed
description Hamartomas are non-neoplastic tissue abnormalities commonly found in various organs but rarely in the upper aerodigestive tract. Respiratory epithelial adenomatoid hamartoma (REAH) is a rare benign proliferation affecting the nasal cavity and sinonasal tract. It often mimics other nasal masses, leading to diagnostic challenges. We present the case of a 25-year-old female with recurrent epistaxis and chronic bilateral nasal obstruction. Diagnostic endoscopy revealed a polypoidal mass, later confirmed as REAH through histopathological examination. CT scans demonstrated soft tissue opacity but no erosion of surrounding bony structures. The patient underwent endoscopic excision, and the excised mass exhibited characteristic histological features of REAH. Endoscopic excision with careful postoperative follow-up can lead to successful outcomes in REAH cases. A year of follow-up revealed no recurrence.
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spelling pubmed-106232002023-11-04 Respiratory Epithelial Adenomatoid Hamartoma in a Young Female: A Diagnostic Dilemma Mujeeb, Abdul Singavarapu, Prathap Reddy Chaganti, Lalitha Alekhya Seelamonthula, Abhishek Sai Kotha, Rakesh Cureus Pathology Hamartomas are non-neoplastic tissue abnormalities commonly found in various organs but rarely in the upper aerodigestive tract. Respiratory epithelial adenomatoid hamartoma (REAH) is a rare benign proliferation affecting the nasal cavity and sinonasal tract. It often mimics other nasal masses, leading to diagnostic challenges. We present the case of a 25-year-old female with recurrent epistaxis and chronic bilateral nasal obstruction. Diagnostic endoscopy revealed a polypoidal mass, later confirmed as REAH through histopathological examination. CT scans demonstrated soft tissue opacity but no erosion of surrounding bony structures. The patient underwent endoscopic excision, and the excised mass exhibited characteristic histological features of REAH. Endoscopic excision with careful postoperative follow-up can lead to successful outcomes in REAH cases. A year of follow-up revealed no recurrence. Cureus 2023-10-04 /pmc/articles/PMC10623200/ /pubmed/37927721 http://dx.doi.org/10.7759/cureus.46453 Text en Copyright © 2023, Mujeeb et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Mujeeb, Abdul
Singavarapu, Prathap Reddy
Chaganti, Lalitha Alekhya
Seelamonthula, Abhishek Sai
Kotha, Rakesh
Respiratory Epithelial Adenomatoid Hamartoma in a Young Female: A Diagnostic Dilemma
title Respiratory Epithelial Adenomatoid Hamartoma in a Young Female: A Diagnostic Dilemma
title_full Respiratory Epithelial Adenomatoid Hamartoma in a Young Female: A Diagnostic Dilemma
title_fullStr Respiratory Epithelial Adenomatoid Hamartoma in a Young Female: A Diagnostic Dilemma
title_full_unstemmed Respiratory Epithelial Adenomatoid Hamartoma in a Young Female: A Diagnostic Dilemma
title_short Respiratory Epithelial Adenomatoid Hamartoma in a Young Female: A Diagnostic Dilemma
title_sort respiratory epithelial adenomatoid hamartoma in a young female: a diagnostic dilemma
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623200/
https://www.ncbi.nlm.nih.gov/pubmed/37927721
http://dx.doi.org/10.7759/cureus.46453
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