Elderly rats fed with a high-fat high-sucrose diet developed sex-dependent metabolic syndrome regardless of long-term metformin and liraglutide treatment

AIM/INTRODUCTION: The study aimed to determine the effectiveness of early antidiabetic therapy in reversing metabolic changes caused by high-fat and high-sucrose diet (HFHSD) in both sexes. METHODS: Elderly Sprague–Dawley rats, 45 weeks old, were randomized into four groups: a control group fed on t...

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Detalles Bibliográficos
Autores principales: Ivić, Vedrana, Zjalić, Milorad, Blažetić, Senka, Fenrich, Matija, Labak, Irena, Scitovski, Rudolf, Szűcs, Kálmán Ferenc, Ducza, Eszter, Tábi, Tamás, Bagamery, Fruzsina, Szökő, Éva, Vuković, Rosemary, Rončević, Alen, Mandić, Dario, Debeljak, Željko, Berecki, Monika, Balog, Marta, Seres-Bokor, Adrienn, Sztojkov-Ivanov, Anita, Hajagos-Tóth, Judit, Gajović, Srećko, Imširović, Alen, Bakula, Marina, Mahiiovych, Solomiia, Gaspar, Robert, Vari, Sandor G., Heffer, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623428/
https://www.ncbi.nlm.nih.gov/pubmed/37929025
http://dx.doi.org/10.3389/fendo.2023.1181064

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