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Lived experiences of students with virological failure on antiretrovirals at a university in Limpopo

BACKGROUND: Human immunodeficiency virus (HIV)-positive students at a rural university in Limpopo province are followed-up according to the national guidelines for the treatment of HIV. Blood monitoring revealed that some students on antiretroviral (ARV) treatment were not virologically suppressed d...

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Autores principales: Maphakela, Mahlodi P., Kekana, Mokoko P., Maimela, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623482/
https://www.ncbi.nlm.nih.gov/pubmed/37916666
http://dx.doi.org/10.4102/curationis.v46i1.2478
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author Maphakela, Mahlodi P.
Kekana, Mokoko P.
Maimela, Eric
author_facet Maphakela, Mahlodi P.
Kekana, Mokoko P.
Maimela, Eric
author_sort Maphakela, Mahlodi P.
collection PubMed
description BACKGROUND: Human immunodeficiency virus (HIV)-positive students at a rural university in Limpopo province are followed-up according to the national guidelines for the treatment of HIV. Blood monitoring revealed that some students on antiretroviral (ARV) treatment were not virologically suppressed despite adherence and compliance being emphasised at every visit. OBJECTIVES: The study sought to identify the students’ experiences that were hindering the viral load from improving. METHOD: A two-phase qualitative, explorative, descriptive study design was followed. Convenience purposive sampling methods were taken on. By means of a semi-structured interview guide, face-to-face interviews were directed. Thematic content analysis was applied. RESULTS: Non-disclosure, noisy ARV packaging, stigma, and service delivery played a role in determining levels of student adherence and compliance with ARVs in the study sample. CONCLUSION: Study findings suggest practical recommendations to improve compliance among students on ARVs: provision of HIV education to all students to help reduce stigma and make it easier to disclose HIV status; use of user-friendly noise-free packaging by pharmaceutical companies to enclose medication, such as blister packs; a supermarket approach in service delivery points to reduce the stigmatising effects of consulting rooms for ARV services. CONTRIBUTION: There is scope to examine the relevance of these findings for other students in the country, to compare them, and to use material from larger studies to guide targeted interventions that could improve adherence among young people.
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spelling pubmed-106234822023-11-04 Lived experiences of students with virological failure on antiretrovirals at a university in Limpopo Maphakela, Mahlodi P. Kekana, Mokoko P. Maimela, Eric Curationis Original Research BACKGROUND: Human immunodeficiency virus (HIV)-positive students at a rural university in Limpopo province are followed-up according to the national guidelines for the treatment of HIV. Blood monitoring revealed that some students on antiretroviral (ARV) treatment were not virologically suppressed despite adherence and compliance being emphasised at every visit. OBJECTIVES: The study sought to identify the students’ experiences that were hindering the viral load from improving. METHOD: A two-phase qualitative, explorative, descriptive study design was followed. Convenience purposive sampling methods were taken on. By means of a semi-structured interview guide, face-to-face interviews were directed. Thematic content analysis was applied. RESULTS: Non-disclosure, noisy ARV packaging, stigma, and service delivery played a role in determining levels of student adherence and compliance with ARVs in the study sample. CONCLUSION: Study findings suggest practical recommendations to improve compliance among students on ARVs: provision of HIV education to all students to help reduce stigma and make it easier to disclose HIV status; use of user-friendly noise-free packaging by pharmaceutical companies to enclose medication, such as blister packs; a supermarket approach in service delivery points to reduce the stigmatising effects of consulting rooms for ARV services. CONTRIBUTION: There is scope to examine the relevance of these findings for other students in the country, to compare them, and to use material from larger studies to guide targeted interventions that could improve adherence among young people. AOSIS 2023-10-30 /pmc/articles/PMC10623482/ /pubmed/37916666 http://dx.doi.org/10.4102/curationis.v46i1.2478 Text en © 2023. The Authors https://creativecommons.org/licenses/by/4.0/Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Original Research
Maphakela, Mahlodi P.
Kekana, Mokoko P.
Maimela, Eric
Lived experiences of students with virological failure on antiretrovirals at a university in Limpopo
title Lived experiences of students with virological failure on antiretrovirals at a university in Limpopo
title_full Lived experiences of students with virological failure on antiretrovirals at a university in Limpopo
title_fullStr Lived experiences of students with virological failure on antiretrovirals at a university in Limpopo
title_full_unstemmed Lived experiences of students with virological failure on antiretrovirals at a university in Limpopo
title_short Lived experiences of students with virological failure on antiretrovirals at a university in Limpopo
title_sort lived experiences of students with virological failure on antiretrovirals at a university in limpopo
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623482/
https://www.ncbi.nlm.nih.gov/pubmed/37916666
http://dx.doi.org/10.4102/curationis.v46i1.2478
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