PLPPR4 haploinsufficiency causes neurodevelopmental disorders by disrupting synaptic plasticity via mTOR signalling

Phospholipid phosphatase related 4 (PLPPR4), a neuron‐specific membrane protein located at the postsynaptic density of glutamatergic synapses, is a putative regulator of neuronal plasticity. However, PLPPR4 dysfunction has not been linked to genetic disorders. In this study, we report three unrelate...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Huanzheng, Zhang, Qian, Wan, Ru, Zhou, Lili, Xu, Xueqin, Xu, Chenyang, Yu, Yuan, Xu, Yunzhi, Xiang, Yanbao, Tang, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623522/
https://www.ncbi.nlm.nih.gov/pubmed/37550884
http://dx.doi.org/10.1111/jcmm.17899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623522/
https://www.ncbi.nlm.nih.gov/pubmed/37550884
http://dx.doi.org/10.1111/jcmm.17899

Ejemplares similares