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Subtle Structural Modification of a Synthetic Cannabinoid Receptor Agonist Drastically Increases its Efficacy at the CB1 Receptor
[Image: see text] The emergence of synthetic cannabinoid receptor agonists (SCRAs) as illicit psychoactive substances has posed considerable public health risks, including fatalities. Many SCRAs exhibit much higher efficacy and potency compared with the phytocannabinoid Δ(9)-tetrahydrocannabinol (TH...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623572/ https://www.ncbi.nlm.nih.gov/pubmed/37847546 http://dx.doi.org/10.1021/acschemneuro.3c00530 |
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por Yano, Hideaki, Chitsazi, Rezvan, Lucaj, Christopher, Tran, Phuong, Hoffman, Alexander F., Baumann, Michael H., Lupica, Carl R., Shi, Lei
Publicado 2023
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Publicado 2023
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Online
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