Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease

Non-familial Alzheimer’s disease (AD) occurring before 65 years of age is commonly referred to as early-onset Alzheimer’s disease (EOAD) and constitutes ~ 5–6% of all AD cases (Mendez et al. in Continuum 25:34–51, 2019). While EOAD exhibits the same clinicopathological changes such as amyloid plaque...

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Detalles Bibliográficos
Autores principales: Valdes, Phoebe, Henry, Kenneth W., Fitzgerald, Michael Q., Muralidharan, Koushik, Caldwell, Andrew B., Ramachandran, Srinivasan, Goldstein, Lawrence S. B., Mobley, William C., Galasko, Douglas R., Subramaniam, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623777/
https://www.ncbi.nlm.nih.gov/pubmed/37924159
http://dx.doi.org/10.1186/s13041-023-01063-5

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