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Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency

BACKGROUND: The monocarboxylate transporter 8 (MCT8) plays a vital role in maintaining brain thyroid hormone homeostasis. This transmembrane transporter is expressed at the brain barriers, as the blood–brain barrier (BBB), and in neural cells, being the sole known thyroid hormone-specific transporte...

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Detalles Bibliográficos
Autores principales: Guillén-Yunta, Marina, Valcárcel-Hernández, Víctor, García-Aldea, Ángel, Soria, Guadalupe, García-Verdugo, José Manuel, Montero-Pedrazuela, Ana, Guadaño-Ferraz, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10623792/
https://www.ncbi.nlm.nih.gov/pubmed/37924081
http://dx.doi.org/10.1186/s12987-023-00481-w

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